Item Room Spawn
Start new games in the item room
This mod will teleport you to the item room as soon as you start a new game. Prevents holding R for 3 days while cheesing it to find an item room attached to the starting room. Only happens on a new save when you spawn on the first floor.

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C:\Program Files (x86)\Steam\steamapps\common\The Binding of Isaac Rebirth\resources\scripts
If you already have main.lua there then you must copy everything from new main.lua and paste it in the bottom of old main.lua file.
Great mod idea!
Go to:
C:\Users\YourNameHere/Documents/My Games/Binding of Isaac Afterbirth+ Mods/
Then:
Put the folder named "ItemRoomSpawn" inside the "Binding of Isaac Afterbirth+ Mods" folder.
It should work after that. Make sure it's enabled ingame.